Özet:

Beta-lactam antibiotics were the first and most common therapy in the treatment of bacterial infections. Multiple resistance emerged and became a major public health problem. To overcome this problem there are several techniques. The main objective of this research is to systematically review and evaluate of b-lactam antibiotic. In this paper, will try to answer the question: what are the techniques and modification that use to enhance drug activity and prevent bacterial resistance. Will start by explaining the meaning of β-lactam antibiotic, then followed by reviewing a type of technique found to decrease bacterial resistance, in the literature review part. It is not in detail, but covers some about b-lactam antibiotic and techniques that overcome the problem of bacterial resistance. Finally, a discussion and the result will be presented to answer the asked question and the conclusion summarizes the reasons why antibiotic resistance is very critical

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