Özet:

Aim: While cervical cancer was at the forefront of female genital cancers until the early 20th century, incidence and death from cervical cancer decreased by 50% due to the spread of cervical cancer screening after the 1950s. Infection with human papilloma virus is the most important factor in the development of cervical cancer. Cervical smear screening is an important method used for early diagnosis of cervical cancer and precursor lesions, especially in developed countries. Materials and Methods: The results of 223 patients who were examined and in the Medical Pathology Laboratory of the Selcuk University Medical Faculty Hospital between 2010-2018, who had a smear result before and who underwent cervical biopsy were compared. Results: The average age of 223 patients was 45 (26-83). Biopsy results: Chronic inflammation in 173 (78%) patients, low-grade squamous intraepithelial lesion in 15 (7%) patients "HPV or mild dysplasia or CIN 1, high-grade squamous intraepithelial lesion in 21 (9%) patients" Moderate dysplasia or level dysplasia or CIN 2 or CIN 3 or Carcinoma has been in situ and in 14 (6%) patients as malignant / squamous cell carcinoma. Conclusion: When the biopsy and smear results were evaluated together, it was observed that the results of biopsy and smears were compatible in 141 (63%) patients, and the results of biopsy and smears were different in 82 (37%) patients. Ease of application and low cost of Pap smear test has made this method widely used. False negative results can be seen due to technical reasons and evaluation errors. In our series, a correlation was found in 63% of cases. Although false negative rates with Pap smear range from 1.1% to 50%, this test is still considered the most effective method for detecting precancerous lesions.

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