Özet:

Objective: Despite all developments in coronary artery bypass surgery; bleeding remains a major problem. Antiagregant drugs, proven by many clinical studies that reduced ischemic heart events, are widely used. While using clopidogrel from these medications, the number of patients taken for emergency and early coronary artery bypass (CABG) surgery also increases. In this study, the effect of preoperative clopidogrel use on postoperative bleeding was studied in patients with emergency and early CABG surgery. In this study, different teams compared the amount of bleeding, the type and quantity of blood transfusion used, with 66 patients who were taken to an emergency and early surgery while using clopidogrel due to coronary artery disease between 2015 and 2017, with 68 patients who were not taken to clopidogrel in elective conditions, the amount of bleeding, the type and quantity of blood transfusion used, according to the number of revisions. Results: 75.4% of the 134 patients we received were male (n:101) and 24.6% (n:33) female. 49.3 percent of patients (n:66) used clopidogrel and 50.7 percent (n:68) did not use clopidogrel. The group using clopidogrel was 410(150-1300) mL, while the other group was 640(150-2750) mL. In the non-clopidogrel group, the amount of post-drenage was statistically significantly higher (P<0.001). When assessed the amounts of fresh frozen plasma and thrombocytes suspension used, the group using clopidogrel was observed to be significantly higher (P<0.001;<0.001). 4.6 percent of 134 patients (n:3) observed revision. One of these three patients was in the group that did not use clopidogrel, while two were in the group that did not use clopidogrel. According to the Fisherexact test, there was no statistically significant difference between them (P:0.616). The result: Emergency and early coronary bypass operations under clopidogrel treatment can be done with accurate blood control and intense use of thrombocytes with acceptable results.

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