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Dev Hücreli Miyokardite Bağlı Ani Ölüm
2010
Journal:  
Acıbadem Üniversitesi Sağlık Bilimleri Dergisi
Author:  
Abstract:

Dev hücreli myokardit genellikle çok ani gelişen, ölümcül seyreden, multinükleer dev hücreler, lenfohistiositik infiltrasyon ve miyosit nekrozu ile karekterize bir hastalıktır. Tanısı genellikle otopsi ile konulabilir. Çalışmada 35 yaşında, tenis oynarken ani ölen kadın olgu bildirilmektedir. Yapılan otopside kalp 315gr. tartıldı. Sol ventrikül duvar kalınlığı 1,4 cm, sağ ventrikül duvar kalınlığı 0,1-0,3 cm ölçüldü. Her iki ventrikülde de papiller kaslarda belirgin düzensizlik, fibrotik görünüm ve sol ventrikülde 4 cm çapında anevrizma izlendi. Her iki ventrikül myokard kesitlerinde de beyaz renkli yaygın fibrozis alanları içinde koyu renkli alacalı görünümde alanlar izlendi. Myokard kesitlerinin mikroskobik incelemesinde geniş alanlarda kas liflerinin yerini alan bağ dokusu, yoğun lenfoplazmositer iltihabi hücre infiltrasyonu, multinükleer dev hücreler ve seyrek eozinofil polimorflar görüldü. Diğer iç organlarda hiperemi dışında mikroskobik bulgu saptanmadı. Bu bulgular eşliğinde olgu idiopatik dev hücreli myokardit olarak değerlendirildi.Sonuç olarak, literatürde de oldukça nadir bildirilen dev hücreli myokardit olgusu, ani ölüm olgularında ayırıcı tanıya alınması gereken bir antite olarak sunulmuştur

Keywords:

A huge cell myocardial death.
2010
Author:  
Abstract:

Gigantic cell myocarditis is a disease that is often very suddenly developing, deadly, characterized by multi-nuclear giant cells, lymphohistic infiltration and myocytic necrosis. It can usually be diagnosed with autopsy. A 35-year-old woman died suddenly while playing tennis. The autopsy of the heart is 315 gr. was discussed. The left ventricular wall thickness is 1.4 cm, the right ventricular wall thickness is 0.1-0.3 cm. In both ventricles, a noticeable irregularity in the papillary muscles, a fibrotic appearance and anevrism in the left ventricle in a diameter of 4 cm were observed. Both ventricular myocard cuts were also observed in the white-colored common fibrosis areas in the dark-colored substrate areas. In the microscopic study of myocard cuts, the joint tissue that replaced muscle fibers in wide areas, intense lymphoplasmosite inflammatory cell infiltration, multinuclear giant cells, and fluid eosinofil polymorphs were observed. There were no microscopic findings in other internal organs except hyperemia. The phenomenon accompanied by these findings was regarded as idiopathic giant cell myocarditis.As a result, the giant cell myocarditis phenomenon, which is quite rarely in literature, is presented as an antidepressant that needs to be distinguishing in sudden death phenomena.

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Acıbadem Üniversitesi Sağlık Bilimleri Dergisi

Field :   Sağlık Bilimleri

Journal Type :   Ulusal

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Article : 1.079
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Acıbadem Üniversitesi Sağlık Bilimleri Dergisi