Özet:

Large cell neuronendocrine cancers (BHNK) in the lungs are highly rare tumors and carry clinical and biological characteristics similar to small cell lung cancer. In this study, we examined our surgical results, prognosis and survival in cases with the histopathological diagnosis of the lungs with the BHNK. Material-Method: between June 2012 and June 2018 recession and pathological diagnoses were as BHNK, one of the 12 events were female, 11 male, the average age was 61,4±7,5(48-74 years) and retrospective. Prognosis, age, gender, history of smoking, tumor diameter, diagnosis methods of treatment, surgical results and survival hospital records were analyzed. Results: In eight cases the tumor was placed in the right hemitoraks, while in four cases the left hemitoraks was placed. In 11 cases, mediastinoscopy and anatomical lungs resection were applied with mediastinal lymph nod disection. A phase of T1 is a phenomenon that, since there is no pathological lymphatic nodes in the mediastend in the computer thorax tomography, without mediastinoscopy, video-assisted lobectomy and mediastinal lymphatic nodes disection were applied. Seven of the cases (58%) were lost during follow-up due to metastasis or tumor progression. The average tumor diameter, the average right-life time, the unhealthy right-life time and the average stay time in the hospital were calculated respectively; 4.4±2.1 cm (distribution 1-8 cm), 17.9±19.04 months (distribution 2-72 months), 15.08±19.6 months (distribution 1-72 months ) and 6.4±3.6 days (4-12 days) respectively. Postoperative mortality has not been observed. Two(16%) cases of complications (atelektacy and wound site infection) were observed. The result: Although it has characteristics similar to small cell liver cancer in terms of treatment and right-life, a complete consensus in the treatment strategy has not been. Curative anatomical resections and oncological treatments that will be accompanied today seem to be the only chance for long-term survival. However, studies involving a wider series of cases concerning these rare tumors are needed.

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