Abstract:

Tuberculosis is still a significant reason of the morbidite and mortality in the worldwide, especially in developing countries. The cases have been increasing in recent years. The usage of first step drugs such as isoniazid, rifampisin, pirazinamid ve ethambutol is essential at least for a six month and drug resistance is an important handicap in the treatment. The multi-drug terapy is , therefore, usually prefered for the treatment of disease to avoid it. The drugs used tuberculosis do have some potential side effects and the most common one is hepatotoxicity at all. In this circumstance, a definite intervals should be given until eliminating of the toxic effects by laboratory studies and then, resumed the terapy. As we have presented in here a case developped hepatotoxicity to revise the effects of the first step anti- tuberculosis drugs during the treatment of a case diagnosed as a cutaneous tuberculosis.

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