Özet:

Background and Aims: More than 95% of colorectal cancers are of adenomatous polyps origin. A large majority of cancers undergo a transition from normal-looking mucosa to adenoma, dysplasia, and eventually carcinoma. In this study, we aimed to investigate the histopathologic features of colonoscopic polypectomy performed in our surgical unit. Materials and Methods: The data from patients who underwent colonoscopic polypectomy between January 2013 and December 2015 in the surgical endoscopy unit at Erzurum Regional Training and Research Hospital were scanned retrospectively from our department data processing database. Results: The rate of polyps in our patients was 16.1%. One hundred and sixty-five (63.5%) of the patients were male, and 95 (36.5%) were female. The mean age was 60.87±13.1 years (24-93 years old). According to polyp location, 42.1% were in the sigmoid colon, and 29.6% were in the rectum. On histopathological evaluation, 49.5% of the polyps were neoplastic polyps. Tubular adenomas were found in 40.2%, tubulovillous adenomas in 4.4%, villous adenomas in 0.6%, intramucosal carcinomas in 1.2%, and adenocarcinomas in 3.1% of these polyps. Dysplasia was observed in 52 (33%) of adenomatous polyps. Of these, 48 (92%) were low-grade dysplasia, and 4 (3%) were high-grade dysplasia. A positive correlation was observed between polyp diameter and dysplasia (p=0.038). All of the patients with high-grade dysplasia were over 50 years old. However, the rate of total dysplasia was higher in younger patients and was statistically significant (p=0.005). Conclusion: In this study, we found that polyp diameter correlates positively with dysplasia in adenomatous polyps, which are cancer precursors, and that total dysplasia is higher in young patients and high-grade dysplasia in elderly patients.

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