Abstract:

This study was aimed at comparing the values of the average thrombocyte volume (MPV) and red blood cell distribution width (RDW) according to the healthy control group of graves patients and whether they have a relationship with cardiovascular risk factors. 50 graves patients and 50 healthy control patients were examined retrospectively. Diabetes mellitus (DM), iron deficiency anemia, chronic kidney injury, hypertension (HT), previously experienced myocardial infarction, congestive heart failure, chronic inflammatory disease, malignity and patients using antihyperlipidemic drugs were not included in the study. At the time of application of the Healthy Control Group, the MPV and RDW values were recorded in the routine in the full blood count before the diagnosis began. The LDL cholesterol (LDL-C), Hdl cholesterol (HDL-C), triglyceride (TG) values, whether or not smoking, size, weight and body mass index (VKI) files were also retrospective. The comparison of MPV and RDW values with the student-t test, the relationship with cardiovascular risk factors was assessed by the pearson correlation test. NOTE: There is no significant difference between the MPV values of patients with Graves and who have not yet started treatment and the MPV values of the healthy control group (p=0.291). When we look at the RDW values between the two groups, the RDW values of gravels were significantly low compared to the control group (p<0.05). When compared the MPV and RDW values between gravitational female patients and female patients in the control group, the MPV and RDW values of female patients in the control group were significantly higher compared to gravitational female patients (respectively p=0.047, p=0.012). There is no correlation between the cardiovascular risk factors of smoking, age and VKI and MPV, RDW values. The gravitational group did not identify the correlation between LDL-C and RDW, while the negative correlation between LDL-C and MPV was identified (p=0.016, r=-0.443). Results: MPV and RDW values, which are considered as inflammation indicators and cardiovascular disease risk indicators, have not been established a relationship with cardiovascular risk factors in serious patients.

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