It is known that the period of Anatolian Principalities is an active phase in terms of sciantific and cultural activities. In this respect the attitudes of the Turkmen Rulers play an important role in protecting and supporting science and scientists. İsa Bey, The Ruler of Aydınoğulları Principality, conformed to the sciantific conventions of the period and gave his full support to Hacı Pasha, who was one of the prominent doctors of the 14th Century İslamic world. Hacı Pasha went to Egypt to be trained and was trained there mainly on medicine, ration and religion. He, also worked as adoctor in Kahire Hospital for some time. Hacı Pasha returning back to Anatolia upon the invitation of İsa Bey, worked as a kadi a teacher in madrasahs in Ayasluk (Selçuk) and Birgi and as a doctor in Aydınoğulları Palace for some time. Hacı Pasha wrote more than ten books on medicine, logic, the Koran and commentary on it both when in Egypt and after his turn to Anatolia. Especially the books he compiled on medicine are very important as being one of the first books written on medicine in this period
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