Özet:

Objective: Ischaemia-modified albumin (IMA) has been frequently studied in recent years in ischaemia-based studies. In this study, IMA changes and postoperative pain were investigated in patients who underwent tourniquet and non-tourniquet knee arthroplasty, and the effect of the tourniquet on pain was investigated quantitatively. Methods: After obtaining institutional review board approval, 64 patients who underwent total knee arthroplasty were divided into two groups: tourniquet and non-tourniquet using the block randomisation technique. Blood was collected at the 15th minute and 24th hour postoperatively. A visual analogue scale (VAS) was used by patients to evaluate their pain. Results: According to the results, a significant correlation was found between VAS scores and IMA levels in the blood taken at the postoperative 15th minute (p<0.001). In addition, the IMA levels were significantly higher in the tourniquet group (p<0.001). Less frequent loss of quadriceps muscle strength, less postoperative pain and avoidance of ischaemia-related complications are the main advantages of non-tourniquet knee arthroplasty. IMA is effective in demonstrating these advantages and can be used for problems such as compartment syndrome, which may be accompanied by muscle damage in the extremity.