Özet:

Metabolic syndrome is one of the main factors for development of diabetes mellitus and cardiovascular diseases. It was shown that earlystage renal injury was developed in cases with metabolic syndrome. Detection of early-stage renal injury and its treatment seem to be good approach for prevention in cardiovascular and all-cause mortality and morbidity. In the study, it was aimed to compare the methods of CystatinC, Tc99m Mag-3 renal scan and microalbuminuria in detecting early stage of renal injury in patients with metabolic syndrome. A significant difference for serum cystatin-c and urinary microalbuminuria between groups was detected. Mean urinary albumin-creatinine ratio and serum cystatin-C level was significantly higher in patient with metabolic syndrome, compared to individuals in control group (26.4 ± 3.8 mg/g versus 4.9 ± 0.9 mg/g; p = 0.005 and 0.76 ± 0.07 mg/dL versus 0.59 ± 0.05 mg/dL; p = 0.002). Results of Tc99m mag–3 renal scan for both right and lest kidneys were similar (R: 49.4 ± 6.3 % versus 51.7 ± 7.1 %, p = 0.113; L: 50.8 ± 4.8 % versus 48.3 ± 5.9 %, p = 0.202). Mean serum hs-CRP (5.1 ± 0.7 mg/dL versus 1.8 ± 0.3 mg /dL; p < 0.001) and uric acid level (6.7 ± 1.1 mg/dL versus 4.6±1.6 mg/dL; p < 0.001) in patients with metabolic syndrome was detected as significantly higher than among individuals in control group

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