Abstract:

Objectives: Iodine deficiency is still considered to be the major etiological factor for endemic goiter. The patho­genesis of the goiter in iodine deficient area caries differ­ent characteristics. The aim of this study investigate the prevalence of thyroid cancers and type of thyroid cancers in surgically treated patients with nodular goiter in Şırnak city where is iodine deficiency region. Materials and methods: Thyroid surgical materials which were sent to our department were screened ret­rospectively from the archives between the years 2009-2010. Thyroid resection was performed on 241 patients with nodular goiter in one year. We evaluated patients who received the diagnosis of thyroid carcinoma with hist­hopatological examination. Results: 222 of our patients (92.1%) female and 19 (7.9%) were male. The youngest patient 16 and the old­est patient was 80 years old and the average age is 40.9 ± 12.8. Histopathological examination of 197 (81.7%) cases of nodular goiter, 31 (12.9%) cases lymphocytic thyroiditis, 13 (5.4%) patients had thyroid tumors. The three tumors on the 2 cases (0.8%) benign, 11 (4.6%) were malignant. As a type of cancer 1 (0.4%) patients, fol­licular carcinoma-oncocytic variant, 10 (4.2%) cases were papillary carcinoma. Conclusions: Iodine deficiency area in the province of Şırnak in patients with nodular goiter who underwent sur­gery for thyroid cancer rate of 4.6%, and most cancers is seen as a type of thyroid papillary carcinoma. Key words: Iodine deficiency, endemic goiter, thyroid cancer

Keywords: