Özet:

Introduction and Objective: To analyze the predictive values of inflammatory indicators in the success of medical treatment in patients diagnosed with tubo-ovarian apse (TOA). Method and Requirements: Reactive Education and Research Hospital in Women's Diseases and Birth Clinic in 2008-2016 years TOA diagnosed with medical and surgical treatment was evaluated as retrospective to 180 patients. Clinical, demographic, laboratory and operational data were provided by examining the medical records of patients. The results were compared by taking blood samples for pre- and post-treatment, C-reactive protein (CRP) and erythrosite sedimentation rate (ESR) measurements for patients under medical and surgical treatment. As parameters for the full blood count, the number of leukocytes, neutrophils, lymphocytes, hemoglobin, hematokrites and platelet values and the neutrophil/lenfocytes rate (NLR) and platelet/lenfocytes rate (PLR) were studied. 99 (55%) of patients were subjected to surgical treatment due to the failure of antibiotic treatment. The average age of patients, the average apse size, the average pre-treatment number of leukocytes, the number of neutrophils, the number of thrombocytes, the rates of NLR and PLR, and the CRP values were higher in the surgically treated group (p<0.001). When the ROC curve was studied in the prediction of medical treatment success, the 6 cut-off value for NLR was statically meaningful (p<0.001, the area under the curve [AUC=0.77], 95% confidence range: 0.698-0.843, sensitivity 71, specificity 74%). The AUC value for PLR was 0.74. According to the ROC analysis, the predictive cut-off value for the medical treatment success for PLR was 165 (74.7% sensitivity and 65.4% specificity). NLR and PLR are cheap and easily calculable indicators that can be correlated with the prognosis of systemic inflammatory diseases. Preoperative NLR and PLR values can contribute to predict the success of medical treatment in TOA.

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