Özet:

Purpose: In patients with pediatric β-talasemia major syndrome (βTM) increased iron load-related organs accumulate iron and causes dysfunction in the organs it accumulates. In our study, we planned to evaluate the iron accumulation in the kidneys in the magnetic resonance imaging (MRG) with the multi-ecogradent eco (ME-GRE) T2* sequence and to show its relationship with the values of the liver, heart T2*, ferritin, estimated glomerular filtration rate (eGFR). Method: The MRG images taken for the accumulation of iron in the liver and heart of twenty-nine pediatric βTM patients were evaluated and the accumulation of iron from the renal parankyms that entered the examination area was measured. Relationships between the liver, heart T2* values, ferritin, and eGFR values were considered. Results: There was no significant difference between the two renal T2* periods (p 0,001). There is no significant correlation between the renal T2* values and eGFR (r = -0,365, p = 0,052). A medium level correlation was found between the renal T2* values and the cardial T2* values (r = 0,568, p 0,001), but no meaningful correlation with the liver T2* values, the liver iron concentration and the ferritin levels (p > 0,05). There was a weak correlation between the renal T2* values and age (r = 0.495, p = 0.006). As a result of the increased iron burden in the body, iron is accumulated in the kidneys. But the effect of iron accumulation on kidney dysfunction alone is still a controversial topic. We believe that the measurements made in the MRG, which is routine for liver and heart iron accumulation, will help diagnose early kidney iron accumulation and prevent kidney dysfunction, so that the adjustment of sequences will also enter the examination area and will not create time and cost losses.

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