Özet:

Background and Aims: Esophageal and gastric cancers are the major causes of mortality and morbidity worldwide. Esophagogastroduodenoscopy is the gold standard method for the diagnosis of these cancers. We aimed to discuss the findings including demographic characteristics, symptoms at presentation, localization of the tumor, and histopathological characteristics of the upper gastrointestinal malignancies detected in the Mush area, Eastern Turkey in the light of relevant literature data. Materials and Methods: A total of 8131 patients who underwent upper gastrointestinal endoscopy between January 2016 and January 2020 at the Endoscopy Unit of Muş State Hospital were retrospectively analyzed, and 72 patients who were diagnosed pathologically with a malignity were examined. Results: Biopsy was performed for 53% of the 8131 patients who underwent esophagogastroduodenoscopy in our endoscopy unit. Histopathology results of 72 (0.88%) patients were to be malignant. Of these cases, 25 had tumor in the esophagus (34.7%) and 47 had it in the stomach (65.3%). Of all, 38 (52.7%) patients were men and 34 (47.3%) were female. The average age of the patients was 64.5±12.4 years. Histopathological analyses revealed that 80% of the patients with esophageal cancer also had squamous cell carcinoma, while 20% had adenocarcinoma. Of the stomach tumors, 85.1% were adenocarcinoma, 10.6% were intramucosal invasive carcinoma, and 4.3% were neuroendocrine carcinoma. Conclusion: The incidence of upper gastrointestinal cancers in the Mush area demonstrated similar characteristics with the reports from some areas in the Eastern Anatolia region, but different characteristics with those from some other areas. We therefore believe that the present study will contribute to the existing information obtained by cancer epidomiology studies conducted in these regions.

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