Özet:

The term “probiotic” was firstly used to denominate microorganisms that have effects on other microorganisms. Antibiotics are used extensively because diseases are the most important factor limiting production and trade in aquaculture. Intensive use of antibiotics causes resistance to antibiotics, adverse effects on human health and many damages in the ecosystem.  In aquaculture, research on the use of probiotics to stabilize the bacterial populations in the water, reduce pathological bacterial load and improve water quality is increasing and the use of probiotics is widespread. Probiotics are single or mixed live microorganism cultures or metabolites there of which promote the development of the intestinal microflora of the host organisms, cause recovery and rapid growth in the oral cavity, gastrointestinal system, upper respiratory tract. On the other hand, probiotics help to detoxify potentially harmful compounds in foods and feed them by feeding them with amylases and proteases, digesting potentially inaccessible elements in the diet, stimulating the production of vitamins and the congestive immune system. For these reasons it is important to identify antibiotic resistant strains and use them in aquaculture. In this study, 13 antibiotics (Kanamycin-K30, Penicillin-P10, Ampicillin-AM10, Erythromycin-E15, Clindamycin-DA2, Rifampin-RA5, Methicillin-ME5, Enrofloxacin-ENR5, Florfenicol-FFC30, Ciprofloxacin-CIP5, Nitrofurantoin-F300, Methicillin-ME5, Trimethoprim/ Sulphamethoxzole-SXT25) and 4 probiotic bacteria (Lactobacillus rhamnosus, Lactobacillus casei, Lactobacillus fermentum, Lactobacillus paracasei) were used. As a consequence; the probiotic bacteria were determinated that L. rhamnosus was resistant to antibiotics of K30, P10, AM10, E15, DA2 and RA5; was intermediate T30 and then it was sensitive EN5, FFC30, CIP5, F300, ME5 and SXT25. L. fermentum was resistant to K30, AM10, DA2, T30, ME5 and RA5İ; was intermediate E15 and CIP5; and then it is sensitive to P10, ENR5, FFC30, F300 and SXT25. L. paracasei tested was resistant to K30, P10, AM10, E15, DA2 and RA5; was intermediate T30; and then it was sensitive to ENR5, FFC30, CIP5, F300, ME5 and SXT25. L. casei in probiotic bacteria used in the aquaculture was found resistant to antibiotics of K30, P10, AM10, E15, DA2, T30 and RA5 were sensitive, was intermediate ME5; it was sensitive to ENR5, FFC30, CIP5, F300 and SXT25.

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