Özet:

It is known that there is a close interaction between angiogenesis and metabolic changes in the heart and skeletal muscle. However, the adventure of angiogenic mobility, which will be revealed by the effect of exercise on these two tissues, has not been fully clarified. For this reason, the present study was prepared in a traditional review type with the aim of examining how cardiac muscle and skeletal muscle tissues, which are exposed to the physical effects of exercise, respond to physiological angiogenesis. The research was obtained from PubMed, Google Scholar, Web of Science and ULAKBİM databases without the limitation of publication year. In the literature review, the publications reached using 4 Turkish keywords (exercise, angiogenesis, heart muscle, skeletal muscle) and their English versions were examined. An in-depth discussion of the role of exercise in promoting angiogenesis, its effect on the mechanism of angiogenesis, and its contribution to angiogenesis in tissue structure may guide the discovery of new therapeutic targets. In this context, the study focused on ongoing research to explain the remodeling mechanisms and physiological effort of exercise-induced angiogenesis in cardiac and skeletal muscle. In the light of the literature review, it can be stated that the effort of exercise in modeling physiological angiogenesis in both cardiac and skeletal muscle is remarkable and can significantly affect the increase in sportive performance in athletes.

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