Görüntüleme
20
İndirme
2
Objectives: The aim of the study was to evaluate the relationship among lower esophageal sphincter pressure (LESP), Helicobacter pylori (Hp), and gastroesophageal reflux (GER). Methods: The retrospective study included patients with isolated hypertensive or hypotensive lower esophageal sphincter (LES) who underwent esophageal manometry in our gastroenterology motility laboratory and had normal manometry results. Demographic characteristics, complaints on admission, upper endoscopy findings, 24-h esophageal pH monitoring results, and presence of Hp in gastric biopsy were evaluated. Results: A total of 1226 patients were included in the study, among whom women comprised 54% of all patients. Mean age was 45.4±13.4 years. Most common presenting complaint was pyrosis (85.4%). Pathological reflux was detected in 61.4% of the patients in 24-h esophageal pH monitoring. Reflux esophagitis was detected in 22.9% and LES laxity was present in 17.4% of the patients. In gastric biopsy, Hp was positive in 40% of the patients. The age of patients with hypertensive LES was significantly higher and female gender and body mass index (BMI) were associated with hypertensive LES. Pyrosis was significantly less prevalent in patients with hypertensive LESP. Esophagitis and LES laxity were significantly more prevalent in patients with hypotensive LES. No significant difference was found among the three groups with regard to reflux and Hp positivity. No significant difference was found between Hp-positive and Hp-negative groups with regard to reflux and reflux esophagitis. Conclusion: No clear relationship was found among LES disorders, GER, and Hp. Moreover, no significant difference was found among LES disorders with regard to GER, while the presence of hypotensive LESP, rather than Hp, was found to be an important factor in the development of reflux esophagitis.
Purpose: We aimed at assessing the relationship between the 24-hour ph meter test of the lower ozofagus sfinkter pressure and the H. pylori. Tools and methods: The data of patients with normal and isolated hypotensive and isolated hypertensive sub-özofagus sfinkter in the manometry is scaned retrospectively. The demographic characteristics of patients, application complaints, top endoscopy findings, 24-hour pH meters results and the presence of H. pylori in abdominal biopsy samples were assessed. A total of 1226 patients were taken to the study. 54% of all patients were women. The average age of the patient was 45.4±13.4. Patients were most frequently applied with pyrozis (85.4%) complaints. In 61.4 percent, a pathological reflux was detected. In 22.9% of patients there was reflux ozofaith. About 40% of patients found H.pylori positive. The age of patients with hypertensive LESB was statistically significantly increased and the hypertensive LESB was significantly higher in women. Pirosis was a significantly fewer complaint in patients with hypertensive LESB. The BMI was statistically significantly higher in those with hypertensive LESB. Ozofathitis and LES calmness were more statistically significantly detected in patients with hypotensive LES. There is no statistically significant difference between the groups in terms of reflus and H.pylori positive. In comparison with patients with H. pylori positive and negative, no significant difference was observed in terms of reflux and reflux ozofaitis. The result: with the normal, hypotensive or hypertensive LES pressure in the ozofagus manometry, gastro-ozofageal reflux and H. There is no clear relationship between pylori. While there is no difference between LES pressures at 24 hour pH meters, the presence of hypotensive LES seems significant in the development of reflux ozofaith than H. pylori. (SETB-2021-12-382)
Alan : Sağlık Bilimleri
Dergi Türü : Ulusal
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