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Objectives: In the current study, we aimed to investigate retinal vascular density and blood flow changes in patients with chronic obstructive pulmonary disease (COPD) using optical coherence tomography angiography (OCTA) (AngioVue Avanti, Optovue). Methods: Thirty eyes of 30 patients with COPD and 30 eyes of 30 healthy controls were evaluated with OCTA. Foveal and parafoveal vessel density, inner retinal and choriocapillary flow area, and foveal avascular zone (FAZ) area were measured and compared between the groups. Results: No statistically significant differences were observed in the outer retinal flow area and choriocapillary flow area measurements between the groups (p=0.609 and p=0.162, respectively). There was no statistically significant difference in FAZ and FAZ perimeter values between the groups (p=0.725 and p=0.820, respectively). Vascular density measurements in the superficial foveal and parafoveal areas were not statistically significantly different between the groups (p>0.05, for all). Deep parafoveal vascular density values of the COPD group were statistically significantly lower than the control group in all investigated areas except the superior and inferior quadrants. Conclusion: The results of our study demonstrated for the first time that vascular density decreased in the parafoveal area due to COPD-related hypoxemia and endothelial dysfunction.
Purpose: Our study aims to investigate changes in retinal vascular dancitis and blood flow in patients with chronic obstructive lung disease (KOAH) with the help of the optical coherent tomography anjiography (OKTA) (AngioVue Avanti, Optovue) device. The tool and method: 30 eyes of 30 patients with KOAH and 30 eyes of the healthy control group of 30 people were evaluated with the help of OKTA. Foveal and parafoveal vascular dancitis, internal retinal and coryocapular blood flow and foveal avascular zone (FAZ) area are measured and compared between groups. Results: There is no statistically significant difference between the external retinal blood flow and the coryocapular blood flow between the groups (p=0.609, p=0.162). There is no statistically significant difference between groups in the perimeter values of FAZ and FAZ (p=0. 725, p = 0.820 ) There is no statistically significant difference between the groups in vascular dancitis measurements in superphysical foveal and parafoveal areas (p>0.05, for all). The values of deep parafoveal vascular dancite, except the superior and inferior, were statistically significantly lower than the control group in the KOAH group in all areas studied. The results of our study showed for the first time that KOAH-related hypoxia and endothelial dysfunction caused vascular dancite loss in the parafoveal area. (SETB-2020-07-118)
Alan : Sağlık Bilimleri
Dergi Türü : Ulusal
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