Özet:

Purpose: Diabetes mellitus (DM) is often found in patients with dermatophytes and candida infections that cause surface skin infections. In this study; in the Laboratory of Micology, a total of 130 samples of skin and nails cut from 80 diabetic patients considered to have a surface fungal infection were studied. Tools and Methods: In the identification of fungal factors; direct microscopic examination, culture and conventional diagnosis methods were used. The identification of the mayas was made with the API ID32C (bioMérieux, France)) kit. The Candida SPP. The anti-fungal sensitivity tests for the discs were assessed according to the CLSI criteria by the disk diffusion method. Results: The average age of 80 patients involved in the study was 57.73±10 (age range; 36-80) and 35 (44%) were men and 45 (56%) were women. In 89 of the 130 skin and nail scratches evaluated in the study, direct microscope was evaluated as positive. In 89 of 54 examples of direct microscope positively detected cultural positivity. Dermatofit species were identified as a single factor in 36 samples (28%) and Candida spp 29 (22%), while 13 samples (10%) were isolated together. Candida spp was found at 27% (18/68), and trichopyton rubrum (T. rubrum) was found at 25.9% (16/62) (P=0.76). T.rubrum and Candida spp were the most frequently detected factors (P=0.49). The most commonly identified Candida species was Candida albicans (C.albicans). Flukonazole resistance C.albicans, C.sake, C. Parapsylosis and C crosses were identified at 31%, 72, 100% and 100% respectively, and voriconazole resistance at 13%, 14%, 25%, 0% respectively (P=0.21, P=0.63 respectively). The most detected fungal pathogens in DM patients were identified as Candida spp, T. rubrum. Due to the high levels of fluconazole and voriconazole resistance in candida species, it is believed that antifungal sensitivity testing is of great importance in non-treatment events.

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