Görüntüleme
10
İndirme
1
Bir Simental inekte rektal fibromatozis Özet: Bu olayda 4 yaşlı Simental ırkı inekte rektum bölgesinde gözlenen çok sayıdaki tümöral kitlelerden dolayı rektal muayeneyi zorlaştıran ve operasyonuna karar verilen fibromatozis olgusunun klinik ve patolojik yönden incelenmesi amaçlandı. Hayvanda doğumu izleyen dönemde rektal muayene yapılmak istendiğinde rektum çevresinde zamanla sayı ve hacimleri artan kitleler gözlendi. En büyüğü 6,5 cm çapında yuvarlak ve 4x3x1,4cm büyüklüğünde oval, çeşitli büyüklükte 14 adet katı esnek kıvamda, beyaz renkli kitlelere rastlandı. Kitlelerin bazıları deri ve çoğunlukla mukoza ile kaplı olduğu dikkati çekti. %10’luk tamponlu formaldehit ile tespit edilerek parafine gömülen ve 5 µm kalınlığında kesitler alınan dokular, Hematoksilen-Eosin (H-E) ve Van Gieson ile ayrıca immunohistokimyasal (İHK) olarak sitokeratin ve vimentin ile boyandı. H-E kesitli dokulardaki tümöral kitlenin tipik anafor tarzında yerleşmiş fibroblast ve fibrositlerden oluştuğu, yapılan İHK boyamada ise vimentin pozitif ve sitokeratin negatif olarak gözlendi. Bu olgudaki gözlenen makroskobik, mikroskobik ve İHK’sal bulgular kaudal rektumda fibromatozis olgusu ile uyumlu bulunmuştur. Anahtar kelimeler: İnek, rektum, fibroma Rectal fibromatosis in a Simmental cow. Abstract:In this case, it was aimed to investigate the clinical and pathological aspects of fibromatosis which make difficult rectal examination due to multiple tumoral masses observed in a 4-year-old Simmental–breed at rectum. Period of after the birth, the masses were seen around the rectal area of the cow when rectal examination was carried out. The number and volume of masses increased with time.The shapes of masses were round and oval and the largest size were 6.5 cm in diameter and 4 x 3 x 1.4 cm respectively. Totally 14 masses, covered with skin and mucosal membrane were found. Cut surface were whitish colored and solid-flexible in consistency. The tissues were fixed with 10% buffered formaldehyde and embedded in paraffin and sections with a thickness of 5 μm were stained with hematoxylen-eosin (H&E) and Van Gieson and immunohistochemical (IHC) with cytokeratin and vimentin.Tumor tissue in H&E sections consisted of fibroblasts and fibrocytes located in the typical herringbonepattern. Tumoral cells were vimentin-positive and cytokeratin-negative in IHC staining.Macroscopic, microscopic and IHC findings, in this case, were found to be consistent with the presence of fibromatosis in the caudal rectum. Key words: Cow, rectum, fibroma
A Simental rectal fibromatosis Summary: In this event, the 4 old Simental breed was aimed at the clinical and pathological study of the phenomenon of fibromatosis that made rectal examination difficult due to the numerous tumor masses observed in the rectum area of the 4 old Simental breed. When the animal was asked to perform a rectal examination in the period following birth, the number and volume of masses around the rectum were observed over time. The largest was round with a diameter of 6.5 cm and oval with a size of 4x3x1.4 cm, with a variety of sizes of 14 square flexible, found in white-colored masses. Some of the masses noted that they were covered with skin and mostly with mucosa. The tissues that were detected with 10% tampon formaldehyde and buried in paraffin and cut in a thickness of 5 μm were painted with Hematoxylene-Eosin (H-E) and Van Gieson as also immunohistochemical (IHC) with citoceratine and vimentin. The tumor mass in the H-E cut tissues consists of fibroblasts and fibrosites placed in the typical anaforic style, while in the IHK painting vimentin was observed positively and citoceratine was negative. The observed macroscopic, microscopic and IHK findings in this case were found compatible with the phenomenon of fibromatosis in the caudal rectum. Keywords: Sheep, rectum, fibroma Rectal fibromatosis in a Simmental cow. Abstract:In this case, it was aimed at investigating the clinical and pathological aspects of fibromatosis which make difficult rectal examination due to multiple tumoral masses observed in a 4-year-old Simmental-breed at rectum. Period of after the birth, the masses were seen around the rectal area of the cow when rectal examination was carried out. The number and volume of masses increased with time.The shapes of masses were round and oval and the largest size were 6.5 cm in diameter and 4 x 3 x 1.4 cm respectively. A total of 14 masses, covered with skin and mucosal membrane were found. Cut surface were white colored and solid-flexible in consistency. The tissues were fixed with 10% buffered formaldehyde and embedded in paraffin and sections with a thickness of 5 μm were stained with hematoxylen-eosin (H&E) and Van Gieson and immunohistochemical (IHC) with cytokeratin and vimentin.Tumor tissue in H&E sections consisted of fibroblasts and fibrocytes located in the typical herringbonepattern. Tumoral cells were vimentin-positive and cytokeratin-negative in IHC staining.Macroscopic, microscopic and IHC findings, in this case, were found to be consistent with the presence of fibromatosis in the caudal rectum. Key words: cow, rectum, fibroma
Alan : Sağlık Bilimleri
Dergi Türü : Uluslararası
Makale Detay 
Benzer Makaleler
PDF Görüntüle
Dergi Bilgisi
Eseri Dinleyin
Alıntı Yap
Bu Sayfayı Yazdırın
Paylaş
Mendeley
