Amaç: Bu çalışmada tek merkezli bir seride kolorektal kanserli hastaların tedavi sonuçları, sağkalım oranları ve sağkalımla ilişkili faktörlerin belirlen- mesi amaçlanmaktadır. Hastalar ve Yöntemler: Şubat 2000-Ekim 2005 tarihleri arasında elektif koşullarda ameliyat edilen ve tamamı histopatolojik olarak teyid edilmiş adenokanser vakaları olan 200 kolorektal kanserli hasta çalışmaya alındı. Hastalarda demografik özellikler, ek hastalıklar, postoperatif komplikasyon- lar ve sağkalım oranları literatür verileriyle de kıyaslanarak değerlendirildi. Bulgular: Küratif cerrahi girişim kolon kanserli hastaların %94.6’sına, rek- tum kanserli hastaların %94.2’sine yapıldı. 85 hastada (%42.5) ek hastalık- lar mevcuttu. Yara yeri infeksiyonu %5, anastomoz kaçağı oranı ise %1.5 oranında görüldü. 5 yıllık sağkalım oranları kolon kanserli hastalarda evre I, II, III ve IV için sırasıyla %96.3, %87.9, %78.9 ve %32 olarak bulunurken, rektum kanserli hastalarda evre I, II, III ve IV için sırasıyla %93.3, %96.4,%82.6 ve %33.3 olarak bulundu. Tartışma: Hastaların beslenme durumlarının düzeltilmesi, yara infeksiyon- larının azlığı, anastomoz kaçağı oranlarının düşük olması, kan transfüzyon- larının preoperatif dönemde yapılması, riskli hastalara venöz tromboemboli proflaksisi yapılması gibi unsurlar postoperatif komplikasyonların daha az olmasına ve peroperatif mortalitenin azlığına katkı sağlayarak sağkalım oranlarını iyileştirebilmektedir. Anahtar kelimeler: Kolorektal kanser, anastomoz kaçağı, yara enfeksiyonu, sağkalım. THE RESULTS OF COLORECTAL CANCER TREATMENT: AN INSTITUTIONAL SERIES OF 200 CASES Purpose: To determine the institutional results of treatment of colorectal cancer, including survival rates and factors related to survival. Patients and Methods: In this study, 200 colorectal cancer patients who were operated on electively between February 2000 and October 2005 were analyzed. Demographic features, comorbid factors, postoperative complica- tions, and survival rates were evaluated. Results: Curative surgery was performed in 94.6% and 94.2% of colon and rectal cancer patients, respectively. Comorbid diseases were present in 85 patients (42.5%). Wound infection and anastomotic leakage were seen in 3% and 1.5% of the patients, respectively. Five-year survival rates were 96.3%, 87.9%, 78.9%, and 32% for colon cancer patients with stage I, II, III, and IV, respectively. The survival rates for rectal cancer were 93.3%, 96.4%, 82.6%, and 33.3% for stage I, II, III, and IV, respectively. Conclusion: Factors such as supporting the nutritional status of patients, blood transfusion in the preoperative period, thromboembolism prophylaxis in high risk patients, low rates of wound infection, and anastomotic leakage may lead to reduced rates of postoperative complications and peroperative mortality, and improve overall survival. Key words: Colorectal cancer, anastomotic leakage, wound infection, ove- rall survival.
Purpose: In this study, a single-centric series of patients with colorectal cancer is aimed at determining the results of treatment, survival rates and factors associated with survival. Patients and Methods: 200 patients with colorectal cancer, which were operated in elective conditions between February 2000 and October 2005 and all of them were histopathologically confirmed cases of adenocancer, were taken to study. In patients, demographic characteristics, additional diseases, postoperative complications and survival rates were also assessed by comparison with literary data. Results: Curative surgery initiative was carried out in 94.6% of colon cancer patients and in 94.2% of rectum cancer patients. In 85 patients (42.5 percent) there were additional diseases. Infection in the wound site was observed at 5%, and anastomose escape rate at 1.5%. The five-year survival rates were 96.3 per cent, 87.9 per cent and 32 per cent for stages I, II, III and IV, while 93.3 per cent, 96.4 per cent, 82.6 per cent and 33.3 per cent for stages I, II, III and IV for rectum cancer. Debate: Correction of the nutritional conditions of patients, lack of wound infections, low rates of anastomose escape, blood transfusions in the preoperative period, risked patients with venous thromboembolysis prophylaxis can improve survival by contributing to the lack of postoperative complications and peroperative mortality. Keywords: Colorectal cancer, anastomosis escape, wound infection, survival. The results of colorectal cancer treatment: an institutional series of 200 cases Purpose: To determine the institutional results of treatment of colorectal cancer, including survival rates and factors related to survival. Patients and Methods: In this study, 200 colorectal cancer patients who were operated on electively between February 2000 and October 2005 were analyzed. Demographic features, comorbid factors, postoperative complica- tions, and survival rates were evaluated. Results: Curative surgery was performed in 94.6% and 94.2% of colon and rectal cancer patients, respectively. Comorbid diseases were present in 85 patients (42.5%). Wound infection and anastomotic leakage were seen in 3% and 1.5% of the patients, respectively. Five-year survival rates were 96.3%, 87.9%, 78. 9%, and 32% for colon cancer patients with stage I, II, III, and IV, respectively. The survival rates for rectal cancer were 93.3%, 96.4%, 82.6%, and 33.3% for stage I, II, III, and IV, respectively. Conclusion: Factors such as supporting the nutritional status of patients, blood transfusion in the preoperative period, thromboembolism prophylaxis in high risk patients, low rates of wound infection, and anastomotic leakage may lead to reduced rates of postoperative complications and peroperative mortality, and improve overall survival. Key words: Colorectal cancer, anastomotic leakage, wound infection, ove-rall survival.
Alan : Sağlık Bilimleri
Dergi Türü : Uluslararası
Benzer Makaleler | Yazar | # |
---|
Makale | Yazar | # |
---|