Abstract:

There is abundance of evidence showingrelationship between sleep, and learning-memory processes and a negative effect of REM sleep deprivationon learning processes. However, there are somecontradictions between the results of these studies. Therefore,in the present study, we aimed to clarify the effect of exposure of long-term REM sleep deprivation on learningand memory in young adult male rats. The study wasperformed with 30 male Wistar Albino rats, being 8month old and performed by generating groups calledsleep deprivation (SD) (n=10), environment control (EC)(n=10) and cage control (CC) (n=10).Rats in the sleep deprivation group were kept awake for 18 hours per dayfor 21 days by sheltering them in the sleep deprivation setup which was in the form of water tank including 14narrow platforms. Rats in the environment control groupwere sheltered in wide platform water tank while cagecontrol rats were sheltered in standard rat cages forequal times to sleep deprivation group. At the end of sleep deprivation exposure, learning and memory wereassessed in Morris water tank. For the parameters usedto evaluate the level of statistical significance was

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