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Özet Amaç: Bu çalışmanın amacı prostat kanserinde transrektal gri skala ultrasonografi (US) bulguları ile tümörlerin malignite potansiyelleri arasındaki ilişkiyi incelemek ve transrektal renkli Doppler ultrasonografinin (RDUS) tanıya olan katkısını araştırmaktır. Gereç ve Yöntem: Çalışmamızda TRUS eşliğinde yapılan biyopsi sonrası prostat kanseri saptanan 63 olgu retrospektif olarak değerlendirilmiştir. Hastaların tümünde gri skala US, RDUS bulguları, serum PSA düzeyleri, patoloji sonuçları karşılaştırılmış ve aralarındaki ilişki araştırılmıştır. Bulgular: Orta diferansiye tümörler daha çok hipoekojenik iken (%69), kötü diferansiye tümörlerin mikst ekojenitede oldukları gözlenmiştir (%58). İzoekojenik tümörlerin tümü iyi ya da orta derece diferansiye grupta yer almışlardır. Toplam 65 kanser odağının 11’inde (%17) Doppler bakıda kanlanma saptanmazken (derece 0), 8’inde (%12) 1. derece ve 46’sında (%71) 2. derece kanlanma izlenmiştir. Lezyonların kanlanma derecesi arttıkça PSA değerlerinin belirgin olarak arttığı belirlenmiştir. Tümörlerin Gleason skorları ile kanlanma dereceleri arasında da önemli bağlantılar tespit edilmiştir. RDUS ile kanlanma saptanmayan lezyonların tamamı iyi ya da orta derece diferansiye kanser grubundadır. Buna karşın belirgin kanlanma saptanan kanserlerin büyük çoğunluğu (%98) orta ya da kötü diferansiye grupta yer almaktadır. Sonuç: Prostat kanseri saptanmasında RDUS’nin gri skala US’ye ilave katkısı bulunmamıştır. Ancak gri skala US ile kuşkulu lezyonların manifest hale gelmesine katkıda bulunduğu gözlenmiştir. Kanserlerin kanlanma dereceleri ile Gleason skorları arasında önemli bağlantılar dikkati çekmiştir. Buna göre RDUS ile belirgin kanlanma gösteren kanserlerin, kanlanmayan ya da minimal kanlanma izlenen kanserlere göre daha yüksek maligniteye sahip oldukları gözlenmiştir.
The purpose of this study is to study the relationship between transrectal grey scale ultrasound (US) findings in prostate cancer and the malignity potential of tumors and to investigate the contribution of transrectal colored Doppler ultrasound (RDUS) to the diagnosis. Method and method: In our study, 63 phenomena of post-biopsy prostate cancer identified in accompanying TRUS were evaluated as retrospective. In all patients, the gray scale US, RDUS findings, serum PSA levels, pathological outcomes were compared and the relationship between them was studied. The findings: While the tumors of the middle differentiation are more hypo-cogenic (69%) the tumors of the poor differentiation are observed in mixed eco-cogenic (58%). All isgoogenic tumors are included in a group of good or medium-degree differences. In total, 11 of the 65 cancer centers (%17) did not detect doppler bleeding (degree 0), 8 (%12) 1 and 46 (%71) 2 degree bleeding. As the level of bleeding of lesions increases, the PSA values have been markedly increased. There have also been significant links between the Gleason scores of the tumors and the levels of bleeding. All injuries that are not detected with RDUS are in the cancer group to a good or medium degree differentiation. Nevertheless, the vast majority (98%) of cancers diagnosed with severe bleeding are in the middle or poor differentiation group. The result: in the detection of prostate cancer, there was no additional contribution to the US in the gray scale of RDUS. But it has been observed that the grey scale has contributed to the manifestation of suspicious lesions with the US. There were significant links between the blood rate of cancer and the Gleason scores. According to this, cancers with clear bleeding with RDUS have been observed to have higher malignity than non-blooded or minimal bleeding followed cancers.
Purpose: The aim of this study is to investigate the relationship between tumoral malignancy potentials and transrectal gray scale ultrasonographic findings in prostate cancer and to investigate the contribution of transrectal color Doppler ultrasonography to the diagnosis. Material and Methods: We retrospectively evaluated 63 patients with prostate cancer who underwent transrectal associated biopsy in our study. In all patients, gray scale ultrasonography, color Doppler ultrasonography findings, serum PSA levels, pathology results were compared and the relationship between them was investigated. Results: While moderately differentiated tumors were more hypoecogenic (69%), poorly differentiated tumors were observed to be mixed echogenicity (58%). All of the isoecogenic tumors were in the good or moderate differentiation group. In 11 (17%) of 65 cancer centers, no blood flow was detected in Doppler US (grade 0). Eight (12%) of 65 patients had first degree blood flow, while 46 (71%) had second degree blood flow. It was determined that the PSA values significantly increased as the degree of vascularization of the lesions increased. Significant correlations were also found between the Gleason scores of the tumors and the blood flow grade. All lesions with no evidence of color Doppler ultrasonography are found in the good or moderately differentiated cancer group. On the other hand, the majority (98%) of the cancers in which significant blood flow is detected are found in the moderate or poorly differentiated group. Conclusion: There was no additional contribution of color Doppler ultrasonography to gray scale ultrasonography in detecting prostate cancer. However, it has been observed that the gray scale ultrasonography contributes to the manifestation of suspicious lesions. Significant links between cancer blood levels and Gleason scores were noted. Accordingly, it has been observed that cancers that show significant blood flow with color Doppler ultrasonography have higher malignancy than cancers that do not have blood or minimal blood supply.
Alan : Sağlık Bilimleri
Dergi Türü : Uluslararası
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