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Evaluation of Prognostic Markers in Cancer-associated Fibroblast Based Sub-groups of Colorectal Cancer
2022
Journal:  
Acta Medica
Author:  
DOI:  
10.32552/2022.ActaMedica.682
Abstract:

Abstract Objective: Stromal cells in the tumor microenvironment (TME) are among the main players of carcinogenesis. Cancer-associated fibroblasts (CAFs) residing in tumor stroma are involved in cancer progression through various mechanisms, supporting tumor growth, cellular motility and invasiveness. The discovery of markers predicting recurrence risk in colorectal cancer (CRC) have led to the generation of several gene panels, including Coloprint. This study aimed to understand the impact of a CAF-rich and a CAF-poor TME on the performance of the prognostic markers in Coloprint.

Keywords:

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2022
Journal:  
Acta Medica
Author:  
DOI:  
10.32552/2022.ActaMedica.682
Citation Owners
Information: There is no ciation to this publication.
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Acta Medica

Field :   Sağlık Bilimleri

Journal Type :   Uluslararası

Metrics
Article : 1.083
Cite : 142
2023 Impact : 0.029
Details
Acta Medica