Özet:

This case study presents the radiological, cytopathological and histopathological description of the giant cell type of a malignant fibrous histiocytoma on the back of a 9-year-old female Angora cat. Latero-lateral and ventro-dorsal thoracic radiographs was taken to evaluate invasion. Radiologically the mass was invasive but had not invaded the bone. Under general anaesthesia, cytopathological samples were taken from the tumour, using the Fine-Needle Aspiration Cytology (FNAC) technique, and were later stained with May-Grünwald Giemsa solution. The surgically extracted biopsy sample was subjected to routine tissue processing and stained with Haematoxylin-Eosin (HE). The biopsy material was 8x6x6 cm and 95 g, was covered by skin, multilobulary appearance and hard consistency. Cross-sections was greyish white and necrotic appearance. Cytopathological examination revealed the presence of numerous histiocyte- or fibrocyte-like cells of anaplastic character and pleomorphic shape, which were associated with giant cells with multiple nuclei and a broad and vacuolar cytoplasm. Histological examination demonstrated the presence of histiocyte-like atypical cells arranged in the form of swirls and extending in various directions, or numerous giant cells with 8 to 12 nuclei and a broad cytoplasm situated in between connective tissue cells.

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