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Papiller tiroid kanserinde karşı paratrakeal lenf bezi metastazı gelişimi ile ilişkili risk faktörleri
2016
Journal:  
Şişli Etfal Hastanesi Tıp Bülteni
Author:  
Abstract:

Amaç: Papiller tiroid kanserinde lenf bezi metastazı sık görülür. Bu çalışmada; papiller tiroid kanserinde karşı paratrakeal lenf bezi metastazı oranı, karşı taraf lenf bezi metastazı için risk faktörleri ve bunların lenfatik diseksiyon alan genişliğine etkilerinin değerlendirilmesi amaçlandı. Gereç ve Yöntemler: Papiller tiroid kanseri tanılı, tiroidektomi ile birlikte santral ve/veya terapötik lateral boyun diseksiyonu uygulanan, ortanca yaş 44 (16-75) olan 27 (19K, 8E) hastanın verileri incelendi. Karşı taraf paratrakeal metastaz gelişimi üzerine yaş, cinsiyet, ekstratiroidal yayılım, multifokalite, bilateralite, lenfovasküler invazyon, T evresi, prelaringeal metastaz varlığı, pretrakeal lenf bezi metastazı, aynı taraf paratrakeal lenf bezi metastazı, lateral metastaz varlığının etkisi değerlendirildi. İstatistik olarak ‘’Ki-kare’’ ve ‘’Fisher’in kesin olasılık’’ testleri kullanıldı. Bulgular: Bu hastalara total tiroidektomiye ek olarak bilateral santral diseksiyon ve 12’sine ek olarak terapötik lateral boyun diseksiyonu uygulandı. T evresi sırasıyla T1: 16 (%59.3), T2: 7 (%25.9), T3: 4 (%14.8) idi. Karşı paratrakeal metastaz gelişimi lateral metastaz (%100 vs %47.6; p=0.05) varlığında anlamlı olarak yüksek bulundu. Sonuç: Papiller tiroid kanserinde lenf nodu metastazı sık olup, öncelikle aynı taraf paratrakeal bölge lenf bezlerinde metastaz ortaya çıkmaktadır. Lateral metastazlı hastalarda karşı taraf paratrakeal metastaz gelişme riski daha yüksektir. Ameliyat öncesi veya peroperatif olarak lateral ve/veya lenf bezi metastazı saptanması, bilateral santral boyun diseksiyonu yapılmasında dikkate alınmalıdır.

Keywords:

Risk factors associated with the development of paratrakeal lymphatic metastasis against papillary thyroid cancer
2016
Author:  
Abstract:

Purpose: In papillary thyroid cancer, lymphatic metastasis is frequent. This study was aimed at evaluating the rate of paratrakeal lymphatic metastasis against papillary thyroid cancer, the risk factors for the opposite lymphatic metastasis and their effects on the width of the lymphatic disection area. Tools and Methods: Papillary thyroid cancer was diagnosed, data of 27 patients (19K, 8E) with an average age of 44 (16-75) who were applied central and/or therapeutic lateral neck disection with thyroidectomy. On the opposite side of paratrakeal metastasis development on age, gender, extratiroidal spread, multifocality, bilaterality, lymphovascular invasion, stage T, the presence of prelaringeal metastasis, pretrakeal lymphatic metastasis, the same side of paratrakeal lymphatic metastasis, the effect of the presence of lateral metastasis was evaluated. For statistical purposes, "Ki-Care" and "Fisher's Certain Probability" tests were used. Results: In addition to total thyroidectomy, these patients were given bilateral central disection and therapeutic lateral neck disection in addition to 12. The T stage was respectively T1: 16 (59.3%), T2: 7 (25.9%), T3: 4 (14.8%). The development of counterparatrakeal metastases was significantly high in the presence of lateral metastases (100% vs. 47.6%; p=0.05). The result: in papillary thyroid cancer, lymphatic nod metastasis is frequent, and metastasis occurs primarily in the lymphatic glands of the same side paratrakeal area. Patients with lateral metastases are at a higher risk of developing paratrakeal metastases. Detection of lateral and/or lymphatic metastases pre-operative or peroperative should be taken into consideration when conducting bilateral central neck disection.

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Şişli Etfal Hastanesi Tıp Bülteni

Field :   Sağlık Bilimleri

Journal Type :   Ulusal

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Şişli Etfal Hastanesi Tıp Bülteni