Özet:

Fungi have a potential of using both as nutritive and medicinal food stuff. Because of containing several therapeutic agents, they are reported to be used for hundreds of years to treat several diseases caused by bacteria, fungi, viruses and parasites. The aim of this study is to determine the in vitro antimicrobial activity of Morchella esculenta (L.) Pers. 1801 and Trametes versicolor (L.) Lloyd 1921. M. esculenta and T. versicolor samples were air dried and extracted by using ethanol. Antimicrobial activity of M. esculenta and T. versicolor ethanol extracts were investigated against several Gram positive and Gram negative bacteria strains, fungal strains, which are either standard or isolated from food and some multi drug resistant (MDR) clinical isolate bacteria namely, Bacillus subtilis DSMZ 1971, Candida albicans DSMZ 1386, Enterobacter aerogenes ATCC 13048, Enterococcus durans, Enterococcus faecalis ATCC 29212, Enterococcus faecium, Escherichia coli ATCC 25922, Klebsiella pneumoniae, Listeria innocua, Listeria monocytogenes ATCC 7644, Pseudomonas aeruginosa DSMZ 5071, Pseudomonas fluorescence P1, Salmonella enteritidis ATCC 13075, Salmonella infantis, Salmonella kentucky, Salmonella typhimurium SL 1344, Staphylococcus aureus ATCC 25923, Staphylococcus epidermidis DSMZ 20044, Staphylococcus aureus (MDR), Escherichia coli (MDR), Klebsiella pneumoniae (MDR), Acinetobacter baumannii (MDR), Proteus vulgaris (MDR), Serratia odorifera (MDR) and Streptococcus pneumoniae (MDR) by using the disk diffusion method. As a result, it was observed that ethanol extracts of M. esculenta has medium to high antimicrobial activity against several Gram positive and Gram negative microorganisms tested, where T. versicolor presented low to high antimicrobial activity.