Özet:

Giriş To investigate the relationship between second-trimester uterine artery Doppler findings and parity in pregnancies with pregnancy-induced hypertension (PIH) and/or small for gestational age (SGA) babies. Yöntem Uterine artery Doppler studies were performed in singleton pregnancies at 20-26 weeks of gestation. The mean uterine artery resistance index and the presence or absence of early diastolic notches was recorded. Diastolic blood pressure >90mmHg after the 20th week of gestation in a previous normotensive women was defined as PIH, and SGA was defined as a birth weight below the 10th centile. Bulgular 288 complicated pregnancies, including 119 cases of PIH were evaluated. Of them, 152 (52.8%) were nulliparous and 136 (47.2%) multiparous. Twenty-nine of the cases (10%) delivered before 34 weeks of gestation. The prevalence of the cases with bilateral notches was significantly higher in of nulliparous women (59.9% vs. 40.4%, p=0.0015). Mean RI measurement was higher in multiparous women (0.58 vs. 0.61, p=0.01). In women with PIH, the percentage of bilateral notches was also higher in nulliparous women (65.6% vs. 43.6%, p=0.026). Mean level of RI was higher in multiparous group (0.58 vs. 0.62, p=0.049). In pregnancies with early preterm delivery, mean RI level did not significantly differ between multiparous and nulliparous women (0.68±0.08 vs. 0.65±0.11, p=0.411) Sonuç The results of our study indicate that in cases with impaired placentation nulliparous women with a higher prevalence of bilateral notches have lower levels of RI. Nevertheless, in cases with early onset of the disease, RI levels were comparable in multiparous and nulliparous women. Analysis of different patterns of Doppler findings in complicated pregnancies may clarify the pathogenesis. Further studies are needed to improve the uterine artery Doppler screening program. 

Anahtar Kelimeler: