Özet:

Background and Aims: In patients presenting with acute upper gastrointestinal bleeding, determining the severity of the disease at the time of admission and making appropriate interventions is very important in terms of prognosis. For this reason, many prognostic scoring systems have been developed. Our aim in this study is to evaluate the ability of admission lactate level to predict in-hospital mortality and to investigate other mortality-related factors. Materials and Methods: The study was conducted retrospectively, including 154 patients admitted with upper gastrointestinal bleeding between March 2020 and March 2023. By evaluating the clinical, demographic and laboratory findings of the patients, independent predictors of in-hospital death were determined and the predictive abilities of these predictors were examined. Results: Of the 154 patients, 99 (64.3%) were male and 55 (35.7%) were female. The mean age of the study population was 67.2 ± 17.8 years. In-hospital mortality occurred in 19 (12.3%) patients. The neutrophil to lymphocyte ratio (OR: 1.149, %95 CI: 1.077 - 1.226), albumin (OR: 0.089, %95 CI: 0.021 - 0.367), and lactate OR: 1.202, %95 CI: 1.031 - 1.402) at admission were determined as independent predictors for in-hospital death. In ROC analysis, the area under the curve for in-hospital death for the combination of albumin, neutrophil-lymphocyte ratio and lactate was 0.974 (%95 CI: 0.950 - 0.998). Conclusion: Admission lactate, neutrophil-lymphocyte ratio and albumin levels were found to be independent risk factors predicting in-hospital mortality.