To review current information and technology for tooth remineralisation. Searches in the "Scopus" and "Web of Knowledge" databases, which date back to 1970s. English was the only language allowed. The study incorporated both original research and previously published reviews. Tooth remineralisation agents, products, and treatments have progressively increased in recent years due to the growing awareness of the significance of good dental health among patients and general community. Both in vitro and in vivo tooth remineralisation and demineralization research have been published regularly. Theobromine has been proposed as an effective remineralising agent and a viable alternative to fluorides in recent years. According to research, fluoride treatments can prevent dental enamel demineralization and remineralisation. An increasing number of products containing calcium salts or calcium-based compounds have been added to oral care products to boost the delivery and retentiveness of fluoride into teeth. Calcium salts or materials, which provide an additional source of calcium, may aid in accelerating enamel remineralisation or hinder demineralization processes. These effects are possible because calcium is a mineral. A new area of research inspired by bioactive materials for bone repair and regeneration, bioglass, in particular calcium silicates, shows promise for improving enamel health and is one type of bioglass that contains calcium silicate.
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