Özet:

INTRODUCTION: The presence of Helicobacter pylori (H. pylori) in biliary tract has recently been discovered. In this study, we aimed to demonstrate the relationship between H. pylori, gallbladder diseases and the upper gastrointestinal symptoms by investigating the presence of H. pylori in the mucosa of the gallbladder and stomach in patients operated for symptomatic cholelithiasis. METHODS: 105 patients underwent cholecystectomy for symptomatic cholelithiasis and underwent upper gastrointestinal endoscopic procedure for dyspeptic symptoms were included to this study. Pathology specimens of the upper gastrointestinal endoscopic biopsy and cholecystectomy were evaluated for the presence of H.pylori using immunohistochemical staining methods with Toludine blue (T. blue) and Warthin starry (W. starry). RESULTS: H. pylori was found to be positive in the gallbladder specimens of 28 patients (26.7%), and in the gastric mucosa of 37 (35.2%) patients. The relation between H. pylori positivity in the gastric mucosa and gallbladder specimens were investigated and found to be not related (p>0.05, r=0.051). H. pylori was also found to be not associated with any specific gallbladder pathology. DISCUSSION AND CONCLUSION: Although the presence of H. pylori in gallbladder was revealed, we are in need of further studies to demonstrate the relation between H. pylori and the formation of gallbladder stones.

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