Abstract:

Objective: Endodontic infections are defined as infections of the periapical tissues. Periapical lesion (apical periododontitis), characterized by the hard tissue resorption and destruction of the periodontal ligament, develops as a result of invasion of the microorganisms in the root canal or their toxins, enzymes and metabolite products out of the root (periapex). In recent studies, it has been reported that oral/periodontal infection and inflammation are risk factors that affect the development and severity of various systemic diseases and conditions. Diabetes mellitus (DM) is one of these common systemic diseases affected by oral infections. The relationship of diabetes with oral and periodontal health has been extensively studied in the literature. However, the pathogenesis, progression and healing process of endodontic infections, which have similar features to periodontal infections, in diabetic patients have not been determined yet. Conclusion: Knowing the relationship between DM and endodontic infections is of great importance in the diagnosis, treatment and follow-up of root canal treatment.

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