Abstract:

The aim of the study is to evaluate changes in serum levels of platelet indices such as average platelet volume (MPV) and platelet distribution width (PDW) in ectopic pregnancy and to investigate whether changes in MPV and PDW have predictive value in ectopic pregnancy. Retrospective analysis of 113 tubal ectopic pregnancies (26 ruptured and 87 unruptured) and 74 healthy pregnant women in the first trimester were included in the study. The hemoglobin, hematocrit, thrombocyte level, MPV, PDW were analyzed. In the result, thrombocyte count was significantly lower in ruptured ectopic pregnancy than in unruptured ectopic pregnancies and control groups (p< 0,01). MPV levels were lower in the ruptured ectopic pregnancy than in the control group, but there was no significant difference between the groups (p = 0.616). PDW levels were higher in ruptured ectopic pregnancy compared to the control group, but there was no statistically significant difference between the three groups (p = 0.451). The platelet counts tend to be lower in ruptured ectopic pregnancy and indicate platelet consumption in the inflamed area. MPV appears to be lower in ruptured ectopic pregnancy, suggesting possible high degree inflammation in the pathology. Our preliminary results suggest that MPV levels may decrease and PDW levels may increase in ruptured ectopic pregnancies. However, further work is needed to define the usefulness of platelet indices in the diagnosis and clinical follow-up of ectopic pregnancies.

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