Özet:

Objective: to identify constitutional and morphological predisposition to acathisia in schizophrenic patients receiving antipsychotic therapy.Materials and methods.250 patients with schizophrenia receiving basic antipsychotic therapy were studied, aged 40 [32; 50] years old; disease duration was 13 [7; 22] years.The age when the schizophrenic process manifested itself was 23 [19; 30] years.Clinical evaluation of acathisia was performed using the Barnes Acathisia Scale (BARS, BAS), so acathisia was detected in 92 (36.8%) patients.All persons included in the study underwent an anthropometric survey according to the Bunak's method.Statistical analysis was performed using Statistica for Windows software (V.12.0), the odds ratio was estimated using the MedCalc online calculator.® The results. The comparative analysis of the Rees - Eysenk body index and Tanner stages in groups of schizophrenic patients receiving antipsychotic therapy with and without acathisia showed no significant differences between them (p = 0.317 and p = 0.347, respectively). Comparison of groups in the distribution of constitutional and morphological types also revealed no statistical differences (p = 0.189). Patients with the andromorphic type of somatic sexual differentiation increased the risk of antipsychotic-induced acathisia (OR = 1.73; 95% CI: 1.02-2.94; p = 0.039) almost twofold. and Conclusion. Attribution of patients to different constitutional and morphological types does not play a role in the development of antipsychotic-induced acathisia, unlike attribution to andromorphic somatic sexual differentiation types, which significantly increases its risk.