Özet:

In development and differentiation, one of the important mechanisms that enables the formation of different cells from cells with the same genetic knowledge is the intercellular signal transmission. At the beginning of this path, Wnt comes. Wnt pathway plays a role in various processes in embryonic development with its effects on embryonic root cells. The effects of the Wnt pathway on embryonic root cells are part of a very complex mechanism. The interactions provided by the micro-environment within the cells can create different responses to the same signal. Pluripotent root cells are of great importance in the field of regenerative medicine. The primary source of these cells are embryonic root cells. But ethical problems prevent the use of these cells. In addition, induced pluripotent root cells, which can be seen as alternate, carry difficulties in production techniques and problems associated with genetic intervention. There is no need for any genetic intervention or attempts to reduce it. There are small molecules that affect different cell mechanisms. One of the mechanisms that are targeted by these molecules is the Wnt signal path. However, a safe and successful method of cellular reprogramming, developed with this pathway, is not yet found.

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