Özet:

Objectives: In this study, we aimed to analyze the effect of the platelet-to-lymphocyte ratio (PLR) and neutrophil-to-lymphocyte ratio (NLR) on prognosis during one-year follow-up after carotid endarterectomy surgery. Patients and methods: Between October 2012 and December 2019, a total of 250 patients (176 males, 74 females; mean age: 67.7±8.8 years; range, 47 to 94 years) with isolated carotid artery endarterectomies were retrospectively analyzed. All patients" data were obtained from the hospital information management system and hospital archive. The patients were divided into two groups (Group 1, n=232 and Group 2, n=18) according to the one-year mortality rate and the risk factors were analyzed. Results: During follow-up, the one-year mortality and one-year no mortality groups were compared. Univariate model revealed that there were statistically significant differences between the groups regarding congestive heart failure, platelet count, NLR, and neurological complications (p<0.05). Additionally, the multivariate model indicated that congestive heart failure, NLR, and neurological complications were statistically different between the groups (p<0.05). Conclusion: Inflammatory and oxidative stress agents play an important role in the prognosis of cardiovascular diseases. The NLR and PLR may be helpful in understanding carotid artery disease and stroke. The NLR levels, preoperative congestive heart failure, and neurological complications in the early postoperative period seem to be the most important prognostic criteria in terms of mortality during one-year follow-up.

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