Özet:

Aim: in our study, we aimed to investigate the potential risk factors in development of obesity and evaluate metabolic syndrome frequency in adolescent population. Material And Methods: We investigated the adolescents with exogenous obesitywho admitted to our clinic between March 2004- December 2005 in terms of gender, gestational age, birth weight, duration of breast-feeding, prevalence of obesity in parents, body mass indices (BMI) of parents, age at onset of obesity and components of metabolic syndrome. Diagnosis of metabolic syndrome was made on the basis of threshold values that were defined by Cruz and Goran considering the data from lllrd National Health and Nutrition Examination Surveys (NHANES). Results:31 obese adolescents (48.4%female, 51.6% male) with the average age of 12.91 ± 2.45 years, and BMI 32.35 ± 5.11 kg/m' were investigated. There was no statistically significant difference in terms of BMI between male and female adolescents (p>0.05). There was also no correlation between birth weight, according to gestational age duration of breast-feeding and BMl's of hoth sexes (p>0.05). There was als no statistically significant difference in BMI of adolescents who have both obese mother and father and who have not (p>0.05).However, there was statistically significant correlation between BMl's of the mother and the child (p<0.01 ). There was also statistically significant correlation between waist circumference and BMI (p<0.05). Blood pressure increased in parallel whit BMI (p<0.05). The frequency of metabolic syndrome was 54.8%. Cholesterol levels were elevated in 32.2%, triglyceride levels were hing in 32.2% and HOL levels were decreased in 25.8%. Glucose intolerance was detected in 25.8% of the cases. There was significant correlation between glucose intolerance and BMI (p<0.01 ). According to homeostasis model assessment insulin resistance (HOMA-IR) index, insulin resistance was >2 in 93.5% ofthe cases. There was statistically significant correlation between BMI and presence of stria as well. 64.5% of the cases had acanthosis nigricans. Conclusion: As in adults, with increasing frequency of obesity, the frequency of clinical pictures related with type il diabetes, like metabolic syndrome also increases. Therefore, obese children especially adolescents that ad mit to general pediatrics and endocrinology outpatient clinics must be investigated in terms of metabolic syndrome criteria and familial risk factors.

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