Özet:

Purpose: In this study, the severity of fibrosis is predicted, the levels of serum aspartate aminotransferase (AST) and area aminotransferase (ALT), the number of platelets, the INR value or the levels of serum hepatitis B virus (HBV) deoxyribonucleic acid (DNA) are meant to be assessed within scores such as AST-platelate ratio (APRI), FIB-4 index and King's score.  Remedies and Methods: Treatment with a biopsy of a beneficial liver injection was considered reverse in naive male HBV patients. In order to assess the difference between the variables, patients were divided into two groups: those with minimal fibrosis (fibrosis score<2) and those with significant fibrosis (fibrosis score≥2).  Results: There were 79 patients with minimal fibrosis (52.7%) and 71 patients with significant fibrosis (42.3%). The optimal value for defining meaningful fibrosis is 4.5 log10 IU/ml for the HBV DNA level (sensitivity: 71.8%, specificity: 70.9%), 0.45 for APRI (sensitivity: 63.4%, specificity: 63.3%), 0.45 for FIB-4 index (sensitivity: 64.8%, specificity: 64.3%) and finally 4.00 for King's score (sensitivity: 67.6%, specificity: 60.8%) In the prediction of the severity of fibrosis in male patients with non-treated HBV infection, the APRI, the FIB-4 index and King's scores are not superior to each other, but the serum HBV DNA levels are slightly better than these scores.

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