Özet:

Purpose: COVID-19 is the result of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) virus infection, which was first isolated and identified in a patient in Wuhan. Although viral pathogenesis is not yet fully known, viral infection is thought to be cytopathic to airway epithelial cells and alveolar cells. In addition, similar to SARS-COV, immune-mediated damage is thought to play a critical role in the pathogenesis of COVID-19. In most patients, the disease progresses with mild to moderate symptoms. The most common findings; symptoms of upper respiratory tract infection including fever, dry cough, malaise, headache, sore throat and myalgia. 20% of the patients show signs of severe lung damage. In the diagnosis of COVID-19, Polymerase Chain Reaction (PCR), serological examination, imaging methods and routine laboratory tests are used. It is thought that determination of laboratory parameters for the diagnosis of COVID-19 will help in the diagnosis, early isolation and early treatment of suspicious cases. Therefore, it was aimed to evaluate complete blood count and biochemical parameters in patient and healthy control groups. Materials and Methods: Fifty patients who applied to the COVID-19 outpatient clinic with early-stage complaints and had a positive PCR test and 50 healthy individuals were included in the study. Biochemical parameters were evaluated retrospectively. 17th edition of SPSS Statistics (IBM Corporation, Somers, NY) software was used for the statistical analysis. Results: A significant difference was found between the patient and control groups in terms of lymphocyte count, monocyte count and CRP parameters. While the lymphocyte count was lower in the patient group, the monocyte count and CRP levels were found to be higher. Conclusion: In line with the data we have obtained; It is considered that especially lymphocyte and monocyte count, CRP values can provide support in terms of diagnosis and follow-up of patients presenting with mild symptoms.

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