Özet:

Helicobacter pylori is a common human patogen implicated in certain gastrointestinal diseases. In the search for new non-invasive techniques to diagnose H. Pylori infection, we evaluated an EIA for H. Pylori antigen in stool (HpSA). In this prospective study, stool specimens from 46 patients (23 women, 23 men; age range 18-70 years, mean 42) undergoing gastroscopy were tested with HpSA, endoscopic biopsies were tested rapid urease test and histological. Patients were defined as positive for Helicobacter pylori if histology and urease test were positive, as negative if histology and urease test were negative. Of 33 patients with H pylori infection by the predefined criteria, 30 were positive by HpSA (sensitivity 90.9 %). Of 13 patients without infection, 11 were negative by HpSA (specifity 84.62 %).

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