Özet:

Purpose: To compare the amount of basal tear secretion and tear film stability in the children with Hashimato’s Thyroiditis (HT) with healthy controls of similar age and gender distribution.Material and Method: Thirty-eight eyes of 19 patients with HT and 38 eyes of 19 healthy controls were included in the study. Duration of HT, presence of any accompanying autoimmune disease (AAD), anti-thyroid peroxidase and anti-thyroglobulin antibody levels were noted in HT group. Presence of dry eye symptoms was asked and Schirmer and tear film break-up time (TBUT) tests were applied. Two groups were compared in terms of these parameters. The relation between the duration of HT, presence of any AAD, anti-thyroid peroxidase and anti-thyroglobulin antibody levels and Schirmer, TBUT test results were evaluated within the study group. Unpaired samples t, chi-square and rank corelation tests were used for statistical analyses.Results: Among the 19 patients with HT, 10 had Type-1 Diabetes Mellitus (DM) and 1 had Celiac Disease. TBUT and Schirmer test results were significantly lower in the study group than controls ((t=24.56, p=0.036; t= 32.54; p=0.027, respectively). Within the study group, TBUT and Schirmer test results were significantly lower in children with an AAD than the ones without (t=11.56, p=0.042; t= 16.56; p=0.039, respectively). No relation was detected between the TBUT, Schirmer test results and the duration of HT, anti-thyroid peroxidase and anti-thyroglobulin antibody level in the study group.Conclusion: The basal tear secretion and tear film stability are lower in children with Hashimato’s Thyroiditis, especially in the ones with accompanying autoimmune disease, than the controls

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