Abstract:

In vitro fertilization (IVF) therapy is the most commonly used assisted reproductive techniques in infertility treatment. The success of live birth rate with assisted reproductive techniques are known about 30% for each embryo transfer. In this study, we aimed to investigate the effects of laboratory parameters and demographic characteristics of couples receiving IVF on oocyte quality, embryo quality and pregnancy rates obtained after infertility treatment. Methods: 455 couples with infertility were included. In the study, 20% of pregnancy group and 63. 7% of non-pregnancy group were evaluated according to their hormonal values with in vitro fertilization parameters, oocyte number, number of fertilized oocytes and embryo quality, fertilization rates and the correlation between the findings were statistically analyzed. Acquired data were analyzed by number, percentage, mean and t-test by chi-square test. Results: In our study, the indications and pregnancy rates of 455 couples diagnosed with infertility were examined. The indications of the couples included in the study were male factor, unexplained infertility and female factors, respectively. When embryo quality was assessed blastomeres were classified according to equal size, round and clear cytoplasm and embryos free of fragmentation. Embryos with a fragmentation rate of 20% were grade I, embryos with increased blastomeric differences were grade II and 20% larger and 50% range embryos with fragmentation grade III, different blastomer number, shape and size, fragmentation rate was more than 50% and blastomer cytoplasms were dark and heterogeneous embryos were selected as grade IV. Follicles obtained from in vitro fertilization patients after controlled ovarian hyperstimulation were collected by oocyte pick-up to separate the granulosa cells around the oocyte. DISCUSSION AND CONCLUSION: The aim of this retrospective study was to investigate the application of drug protocols and in vitro fertilization parameters.

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