Abstract:

Aim: Although blood pressure abnormalities are frequently encountered in patients with polycystic ovary syndrome (PCOS), the relationship between hypertension and PCOS has not been fully elucidated. Our aim of this study is to investigate BP alteration in patients with PCOS according to the new classification proposed by ACC/AHA guideline. Material and Methods: In this study, we compared the BP measurements and baseline characteristics of 64 patients with PCOS and 61 patients without PCOS in the same age group. Results: Compared with the control group, PCOS patients had increased Ferriman Gallwey score (p<0.0001), mean diastolic blood pressure (p=0.0099), glucose levels (p=0.0049), leukocyte counts (p=0.0319), neutrophil counts (p=0.0364) and LH levels (p=0.0018). When the PCOS and Control patients were classified according to the ACC/AHA guideline, 59.4% of the PCOS patients had abnormal BP, while 47.5% of the patients in the control group had abnormal BP. There was a statistically significant differences between the groups (p=0.0343). The correlation analysis showed that there were positive correlation between DBP levels and BMI, serum glucose level, HOMA-IR, total cholesterol and LDL cholesterol in PCOS patients. In addition, there was a negative correlation between DKB and HDL cholesterol levels in PCOS patients. Conclusion: It has been determined that BP (especially DBP) levels tend to increase in PCOS patients in the reproductive period in relation to the presence of insulin resistance, hyperandrogenemia and dyslipidemia, but there is no difference in the incidence of hypertension between PCOS and control groups.

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