Abstract:

INTRODUCTION: Primary infections caused by rubella, cytomegalovirus, toxoplasma can lead to serious complications in pregnancy. Aim of this study was to determine the prevalence of rubella, cytomegalovirus, toxoplama, Hepatitis B virüs, Hepatitis C virus, HIV among pregnant women. METHODS: The study was carried out in Muğla Sıtkı Koçman University Medical School, Department of Obstetrics and Gynecology between June 2014-February 2015. 191 pregnant women for Toxoplasmosis, 189 pregnant women for Rubella, 136 pregnant women for cytomegalovirus and 333 pregnant women for Hepatitis and HIV,aged 18-44 years were enrolled in this study. The results of the serological screening tests during the first trimester of pregnancy were evaluated. RESULTS: Anti-IgG against rubella was found in 170 pregnant women (89,5 %) and rubella IgM in 1 woman (0,8 %). The positivity for anti- cytomegalovirus IgG antibody was found in 123 women ( 90,4 %), while 1 (0,3 %) was positive for the anti-cytomegalovirus IgM antibody. Anti-IgG against toxoplasma was found in 36 women (18,8 %) and toxoplasma IgM in 7 women (3,7 %). The positivity for HbsAg was found in 5 women (1,8 %), while 78 women (23,7 %) were positive for the anti-HbS. The positivity for Anti Hepatitis C virus antibody was found in 1 (0,3 %) woman. No any women was detected for Anti HIV pozitivity. DISCUSSION AND CONCLUSION: Treatment of toxoplazmosis in the fetus and infant during the first year of life has been demonstrated to improve the outcome. Serological screening of pregnant women is the most reliable and currently available strategy for the prevention, diagnosis, and early treatment of the infection in the offspring. Rubella status should be investigated before pregnancy and seronegative females can be advised vaccination. HBsAg screening should be recommended until whole society is vaccinated. Limiting, cytomegalovirus, Hepatitis C virus and HIV screening to high risk group might be appropriate.

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