Özet:

Purpose: In this study, the effects of corn syrup on the lungs in rats feeding with high levels of fructose were studied. Tools and Methods: Twenty-four Wistar Albino female rat were divided into 3 groups. Group 1: Egyptian syrup diet (10 weeks 30% oral), Group 2: Egyptian syrup diet + Alpha Lipoic Acid (ALA) (100 mg/kg, after 4 weeks oral) Group 3: Control group. After the test, changes in the rats' lungs were histopathologically assessed. The blood samples measure the levels of malondialdehitis (MDA) and catalase. The data obtained in three groups were compared using Kruskal Wallis, Mann Whitney-U and ANAVO post-master Bonferroni tests. Results: In the assessment of the histopathological (hyperemia, swelling, lymphatic tissue hyperplasia and inflammatory reaction) of the lung tissue, there was a statistically significant difference between the groups (p=0.004). Histopathological changes are increasing, especially in Group I, while changes in Group II. It was reduced in the group. There is no statistically significant difference between Group I and Group II (p=0.057). Although the blood MDA levels differ between groups (p<0,005) there was no statistically significant difference between groups (p>0.05). In rats fed with Egyptian syrup, it has been found that Egyptian syrup causes histopathological changes in the lungs and that ALA has a healing effect on these lesions in the lungs. But advanced studies are needed to show which mechanism the eggs shurbs affect the lungs.

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