Abstract:

The aim of this study is to investigate the effects of Gingko Biloba extract (EGb761) supplement on hemato-biochemical parameters after acute running band exercise in rats. Thirty-two male rats were divided into four groups with equal numbers of rats. Animals from control and exercise groups were given oral 2 cc/kg and 0.9% of serum for 4 weeks for 5 days/week, while EGb761 and EGb761+ non-exercise groups were given 100 mg/kg and EGb761 with oral garment. On the last day of the trial, acute fatigue exercises were performed on the animals of the exercise groups and blood samples were collected from all the animals from the heart. After the hematological analysis, plasma samples were allocated for biochemical analysis. The results showed that the exercise, EGb761 supplement or both of them did not change the erythrosite (RBC), hematokrit (PCV), hemoglobin (HGB), average alyva hemoglobin (MCH) and average alyva hemoglobin concentration (MCHC) (P> 0.05). However, acute fatigue workout in rats reduced the average alloy diameter (MCV) while increasing the alloy distribution width (RDW) (P<0.05). In addition, the activity of plasma area’s aminotransferase (ALT), total cholesterol and total protein levels did not change in any group (P>0.05) and the activity of alkaline phosphatase (ALP) significantly increased in exercise groups, while glucose and triglyceride levels decreased (P<0.05). As a result, our findings have shown that acute fatigue exercises affect MCV and RDW values, plasma ALP activity, glucose and triglyceride levels. Gingko Biloba extract supplement has improved changes in exercise only in ALP activity and RDW value. Therefore, it was recommended that the effects of post-exercise use of EGB761 or its different doses were examined in extensive studies to be conducted in the future.

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