Background and Objectives:Rheumatoid arthritis (RA) is a symmetric inflammatory polyarticular arthritis, where autoimmune response causes chronic inflammation and destruction of joints leading to deformities and affecting the activities of daily living. ACR recommends early diagnosis and aggressive treatment of RA with combination disease modifying anti-rheumatic drugs (DMARDs). Although it attenuates disease progression, long-term remissions have not been adequately achieved. Injection of platelet rich plasma(PRP) decrease joint inflammation by modulating synovial cell proliferation, differentiation and inhibition of catabolic pathways.
Alan : Sosyal, Beşeri ve İdari Bilimler
Dergi Türü : Uluslararası
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