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Cleft lip and palate represents a group of malformations with multifactorial etiology. Here, its etiology has been reviewed in light of the current literature with the presentation of a case of familial nonsyndromic cleft lip and palate. We present the case of one of the dizygotic twins with cleft lip and palate who applied for our clinic in November 2011. 1 year old female patient presented with bilateral primary and secondary complete cleft lip and palate. The other twin brother and 11-year-old sibling underwent cleft lip repair surgery with the same diagnosis in another clinic. Parents and other family members were unaffected. Cleft lip and palate is the most common craniofacial congenital deformity and is associated with multifactorial etiology. The family must be informed about the familial patterns of inheritance and probability of occurrence in subsequent offsprings.
The etiology of the lips and spine is multifactoral. In this article, a non-syndromic family-based mouth swelling phenomenon is presented together with the study of mouth swelling etiology in the light of current studies. In November 2011, one of the dizigotic twins presented to our clinic with a mouth and spine scratch. In one of the digotic twins, it was found to have bilateral primary and secondary complete lips and spine. One of his ten-year-old brothers and twins was previously operated with the same diagnosis. It was found that no other person in the family had no lips. Craniofasial congenital deformity is the most common in the lips and spine, and many factors play a role in the etiology. The family should be informed that this deformity is a genetic substructure and may also appear in subsequent pregnancies.
Field : Sağlık Bilimleri
Journal Type : Uluslararası
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