Özet:

Toxoplasma gondii (T. gondii) is a mandatory cellular parasite and is as a significant cause of morbidity and mortality in congenital pathways and immunosuppressive patients. In this study, it was aimed at determining the conditions of seropositivity of T. gondii in various age and patient groups, as well as to identify the current immune status, especially in risk groups. Methods: T. gondii serology results studied between 2015-2019 in a medical microbiology laboratory at a university hospital have been reversed. In the study, anti-T. gondii IgM, anti-T. gondii IgG antibodies and anti-T. gondii IgG avidite test results were studied using the enzyme-linked fluorescent assay method. The rates of seropositivity in immunosuppressive patients with toxoplasmosis risk groups and pregnancies have also been shown. The groups with severe immunosuppressions in the identification of immunosuppressive patients have been determined by reverse files. Results: T. gondii serology was studied in a serum sample of 20,875 people, including 6,220 (29,8%) men and 14,655 (70,2%) women in the specified time range. The anti-T. gondii IgM and IgG positivity rates were significantly higher in women compared to men. In all the years, 16,448 patients with IgM and 4,427 patients with IgG positivity were studied. In the five-year period, the seropositivity of T. gondii IgM in all patients was 2.4%, and the seropositivity of T. gondii IgG was 24.1%. Women in the fertility age. The gondii IgG seropositivity rate was 36.1 per cent; 42.4 per cent in pregnancies, 14.6 per cent in immunosuppressive patients. In pregnancy, and especially in the context of the reactivation of latent infection, the need for tracking T. gondii serology in immunosuppressed patients should be considered, toxoplasmosis in suspicious clinical cases should be considered.

Anahtar Kelimeler: